MicroRNA Expression Profiles in the Management of Papillary Thyroid Cancer
نویسندگان
چکیده
منابع مشابه
MicroRNA Expression Profiles in Papillary Thyroid Carcinoma, Benign Thyroid Nodules and Healthy Controls.
MicroRNAs (miRNAs) represent a class of short endogenous non-coding RNAs that negatively regulate gene expression at the post-transcriptional level in many biological processes, including proliferation, differentiation, stress response and apoptosis. In this study we analyzed a set of seven miRNA molecules in sera of patients with papillary thyroid cancer, multinodular goiter and healthy contro...
متن کاملMicroRNA expression profiles in thyroid tumors.
MicroRNAs (miRNAs) constitute a recently identified class of small endogenous noncoding RNAs that act as negative regulators of the protein-coding gene expression and may impact cell differentiation, proliferation and survival, i.e., all fundamental cellular processes implicated in carcinogenesis. miRNA expression is deregulated in many types of human cancers, including thyroid cancer. The purp...
متن کاملManagement of papillary thyroid cancer.
Papillary thyroid cancer is predominantly a sporadic disease that usually presents as an asymptomatic thyroid mass in a euthyroid patient. Irradiation to the neck during childhood significantly increases the subsequent risk of this cancer; the prognosis for radiation-related cancers is similar to spontaneous cases. Physical examination, thyroid scanning and ultrasound, and fine-needle aspiratio...
متن کاملIntegrated analyses of microRNA and mRNA expression profiles in aggressive papillary thyroid carcinoma.
microRNAs (miRNAs) are involved in the pathogenesis of diverse human cancers through its target genes, including papillary thyroid cancer (PTC). However, there are few studies regarding associations between clinicopathological features of PTC with the expression of specific miRNAs and its potential target genes. In the present study, analysis of miRNA was integrated with mRNA expression profile...
متن کاملIncidence of thyroid papillary cancer in contralateral lobe
Background & objectives: Prognosis of thyroid papillary cancer is quite well long lasting, so a 10- year survival is observed in more than 90% cases. In this study, rate of incidence of thyroid papillary cancer in contralateral lobe was assessed among patients who had a surgical thyroidectomy re-operation. Materials & Methods: In this retrospective study, we examined 82 patients diagnosed with...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 2014
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.2014-0135